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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCC
All Species:
14.55
Human Site:
S181
Identified Species:
24.62
UniProt:
Q15814
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15814
NP_003183.1
346
39220
S181
A
E
G
D
L
G
P
S
W
V
C
G
F
S
N
Chimpanzee
Pan troglodytes
XP_518477
346
39236
S181
A
E
G
D
L
G
S
S
W
V
C
G
F
S
N
Rhesus Macaque
Macaca mulatta
XP_001088723
346
39322
S181
A
E
G
D
L
G
S
S
W
V
C
G
F
S
N
Dog
Lupus familis
XP_538923
388
42549
G223
E
G
G
G
I
G
S
G
F
V
F
G
F
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCN9
341
38106
S176
E
E
G
A
P
G
A
S
W
A
C
G
F
S
N
Rat
Rattus norvegicus
NP_001101670
340
38058
S175
E
E
G
A
P
G
A
S
W
A
C
G
F
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508991
335
37102
D170
P
A
A
E
E
P
P
D
D
A
A
G
F
S
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922489
350
39443
A176
G
T
V
V
V
D
A
A
D
Q
C
G
F
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722959
355
40503
N166
V
P
E
K
L
G
S
N
F
T
W
T
I
A
N
Honey Bee
Apis mellifera
XP_001120828
342
39209
D177
K
L
S
S
K
Y
G
D
S
A
C
M
L
L
G
Nematode Worm
Caenorhab. elegans
Q27249
256
29613
K100
D
E
A
D
R
A
R
K
S
M
E
T
R
S
Q
Sea Urchin
Strong. purpuratus
XP_783718
353
39965
E188
Q
P
S
K
I
I
T
E
N
A
A
G
F
V
N
Poplar Tree
Populus trichocarpa
XP_002307082
324
36492
D159
H
I
P
Q
S
I
R
D
S
P
G
I
R
N
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195702
345
38291
R176
P
P
K
L
V
P
V
R
D
S
P
G
L
R
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.3
72.9
N.A.
76
74.5
N.A.
61.5
N.A.
N.A.
43.7
N.A.
33.5
38.7
21.1
39.6
Protein Similarity:
100
99.1
97.6
78.3
N.A.
84.3
83.5
N.A.
74.5
N.A.
N.A.
64
N.A.
57.7
58
40.1
62.6
P-Site Identity:
100
93.3
93.3
46.6
N.A.
66.6
66.6
N.A.
26.6
N.A.
N.A.
33.3
N.A.
20
6.6
20
20
P-Site Similarity:
100
93.3
93.3
60
N.A.
66.6
66.6
N.A.
40
N.A.
N.A.
46.6
N.A.
40
6.6
26.6
26.6
Percent
Protein Identity:
29.7
N.A.
N.A.
32.3
N.A.
N.A.
Protein Similarity:
48.2
N.A.
N.A.
51.7
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
15
15
0
8
22
8
0
36
15
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% C
% Asp:
8
0
0
29
0
8
0
22
22
0
0
0
0
0
8
% D
% Glu:
22
43
8
8
8
0
0
8
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
8
0
65
0
0
% F
% Gly:
8
8
43
8
0
50
8
8
0
0
8
72
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
15
15
0
0
0
0
0
8
8
0
0
% I
% Lys:
8
0
8
15
8
0
0
8
0
0
0
0
0
0
8
% K
% Leu:
0
8
0
8
29
0
0
0
0
0
0
0
15
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
72
% N
% Pro:
15
22
8
0
15
15
15
0
0
8
8
0
0
0
0
% P
% Gln:
8
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% Q
% Arg:
0
0
0
0
8
0
15
8
0
0
0
0
15
8
0
% R
% Ser:
0
0
15
8
8
0
29
36
22
8
0
0
0
65
0
% S
% Thr:
0
8
0
0
0
0
8
0
0
8
0
15
0
0
0
% T
% Val:
8
0
8
8
15
0
8
0
0
29
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
36
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _